Glycine Molecular Structure
Glycine is a Non-Essential Glucogenic Amino Acid. This means that it can be manufactured within the body and through the process of Gluconeogenesis, can be converted into Glucose (sugar). Unlike other amino acids, Glycine is not only a building block used to make other proteins but also influences chemical signal transmission within the Brain. Glycine benefits sugar metabolism and is an essential component of Glucose Tolerance Factor (GTF) which makes it useful for treating Blood Sugar disorders such as Diabetes and Hypoglycemia. This amino acid has a sweet taste and can be used to sweeten beverages.
While research into the virtues of Glycine supplementation is ongoing, a 2017 investigation of its benefits stated: “Oral supplementation of glycine with proper dose is very successful in decreasing several metabolic disorders in individuals with cardiovascular disease, various inflammatory diseases, cancers, diabetes, and obesity. More research investigations are needed to explore the role of glycine in diseases where proinflammatory cytokines, reperfusion or ischemia, and free radicals are involved. Mechanisms of glycine protection are to be completely explained and necessary precautions should be taken for safe intake and dose. Glycine holds an enormous potential in enhancing health, growth, and well-being of both humans and animals.”
Metabolic Functions of Glycine
The Health Benefits of Glycine:
CARDIOVASCULAR SYSTEM
• May alleviate Hypertension (High Blood Pressure).
• Administered sublingually within six hours on the onset of Ischemic Stroke, may reduce mortality in Stroke patients.
• Can increase the survival rate in persons that are in a state of Shock.
• Facilitates the production of Hemoglobin.
• May be useful in the treatment of Sickle-Cell Anemia.
DIGESTIVE SYSTEM
• May help to treat/prevent such Gastrointestinal Issues such as:
▪ Colitis
▪ Crohn’s Disease
▪ Ulcerative Colitis
▪ Hypochlorhydria (low Stomach Acid)
IMMUNE SYSTEM
• Helps reduce Inflammation.
• Liver Cancer may be prevented by supplementation.
METABOLISM
• Facilitates the production of Energy within the body by stimulating the release of Glucose into the bloodstream.
• Fatigue may be alleviated by supplementation, paradoxically, excessive Glycine intake causes Fatigue.
• Hypoglycemia (low Blood Sugar) may be alleviated by supplementation.
• May accelerate the recover from Alcohol (ethanol)-induced Liver damage.
• Stimulates both Insulin and Glucagon production making it useful to help balance Blood Sugar.
• 4,000 – 8,000mg taken at bedtime helps facilitate the release of Human Growth Hormone (hGH).
• Essential for the endogenous production of Glutathione.
MUSCULOSKELETAL SYSTEM
• Up to 30 grams per day may be a useful adjunct therapy for Gout as Glycine stimulates the excretion of Uric Acid from the body.
• 5 – 12 grams per day may stimulate the release of Human Growth Hormone (hGH).
• Can increase Muscle Strength and improve Muscle Tone in persons afflicted with Nervous System disorders.
• Muscular Dystrophy may be improved by supplementation.
• Rheumatoid Arthritis may be prevented by supplementation.
NERVOUS SYSTEM
• By acting as a Norepinephrine Antagonist, may be useful in the treatment of Anxiety and Panic Disorder.
• Functions as an Inhibitory Neurotransmitter and thus may be helpful in conditions such as: Epilepsy, Insomnia, Muscle Spasms and Schizophrenia.
• Can alleviate some of the symptoms of Multiple Sclerosis.
• Interacts with N-methyl-D-aspartate (NMDA) Receptors in the Brain and may be involved in the potentiation of Long- Term Memory.
• By stimulating the production of Endorphins, may be useful in the treatment of Pain.
• Can assist an under-functioning Pituitary Gland.
• The Rapid Eye Movement (REM) stage of Sleep may be enhanced by supplementation.
SEXUAL SYSTEM (Male)
• Helps improve the health of the Prostate Gland.
• When used in combination with Alanine and Glutamic Acid, helps to minimize the symptoms of Benign Prostatic Hyperplasia (BPH).
SKIN
• Concentrates in the Skin and helps to improve its health.
• May accelerate the healing of Wounds.
• Collagen is comprised of 33% Glycine which makes it important for tissue repair.
How Glycine Benefits The Immune System
USAGE
The average daily intake of Glycine from dietary sources is 3 – 5 grams. Dosages of up to 30 grams per day have been used without incident for various health conditions. When using Glycine for an enlarged Prostate it must be combined with Alanine and Glutamic Acid. The dosage used in research studies for treating enlarged Prostate is 780mg per day of Glycine, Alanine and Glutamic Acid for 14 days, then 380mg of each per day thereafter. When using larger doses of Glycine it is best to space them throughout the day. The powder form of Glycine is generally more economical when working with higher doses.
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